A Randomised Controlled Trial of a Duodenal-Jejunal Bypass Sleeve Device (EndoBarrier) Compared with Standard Medical Therapy for the Management of Obese Subjects with Type 2 Diabetes Mellitus
Endoscopically placed duodenal-jejunal bypass sleeve devices, such as the EndoBarrier (GI Dynamics, Lexington, Massachusetts, USA), have been designed to create an impermeable barrier between chyme exiting the stomach and the mucosa of the duodenum and proximal jejunum. The non-surgical and reversible nature of these devices represents an attractive therapeutic option for patients with obesity and T2DM by potentially improving glycaemic control and reducing their weight.